SLU-PP-332 5MG

SKU: SLUPP332-5MG   |   Category: Research Compounds

ERRα/ERRβ/ERRγ pan-agonist | Estrogen-related receptor small molecule | Metabolic research | ≥99% purity

SLU-PP-332 is a synthetic small molecule pan-agonist of the estrogen-related receptor (ERR) family, demonstrating agonist activity at ERRα, ERRβ, and ERRγ. ERRs are orphan nuclear receptors that regulate mitochondrial biogenesis, oxidative phosphorylation, fatty acid oxidation, and energy metabolism without known endogenous steroidal ligands, making them targets for chemical biology research.

Research applications include ERR transcriptional activation assays (reporter gene, FRET-based coactivator recruitment), mitochondrial biogenesis studies via PGC-1α coactivation, OXPHOS gene expression profiling in skeletal muscle and cardiac cell models, fatty acid oxidation flux analysis, and comparative selectivity studies against classical estrogen receptors (ERα, ERβ) to confirm ERR specificity. SLU-PP-332 is an important chemical probe for isolating ERR-mediated biology from ER-mediated pathways.

5mg per vial. Manufactured in ISO 9001 certified facilities under GMP conditions. Purity independently verified at ≥99% by HPLC via ISO/IEC 17025 accredited laboratory. Full COA available.

Storage: Store at -20°C, desiccated, protected from light. Soluble in DMSO.

⚠ For laboratory research use only. Not for human or animal consumption.