SEMAX 10MG

SKU: SEMAX-10MG   |   Category: Research Compounds

ACTH(4-7)-Pro-Gly-Pro heptapeptide | Neuropeptide | BDNF/VEGF signaling model | ≥99% purity

Semax (Met-Glu-His-Phe-Pro-Gly-Pro) is a synthetic heptapeptide analog corresponding to the ACTH(4-7) fragment with a C-terminal Pro-Gly-Pro extension. Unlike the parent ACTH fragment, Semax does not possess adrenocorticotropic activity, making it a cleaner tool for studying peptide effects on neurotrophic signaling pathways independent of HPA axis activation.

Research has focused on Semax-induced BDNF (brain-derived neurotrophic factor) and VEGF upregulation in cortical and hippocampal neuronal cultures, its effects on NGF expression and serotonin receptor density, dopaminergic and enkephalinergic system interactions, and investigation of neuroprotective mechanisms against hypoxic and ischemic insult in cell culture models. Its ACTH backbone provides a useful structural comparator for melanocortin peptide SAR studies.

10mg lyophilized per vial. Manufactured in ISO 9001 certified, GMP-compliant facilities. Purity independently verified at ≥99% by HPLC via ISO/IEC 17025 accredited laboratory. Full COA available.

Storage: Store lyophilized at -20°C. Reconstituted: 4°C, use within 21 days.

⚠ For laboratory research use only. Not for human or animal consumption.